AAT Bioquest 钠离子荧光探针SoNa 520 货号21320

产品参数

Ex (nm)	491	Em (nm)	511
分子量	N/A	溶剂	DMSO
存储条件	在零下15度以下保存, 避免光照

产品概述

产品基本信息

产品名称：钠离子荧光探针SoNa 520

储存条件：-15℃避光防潮

保质期：12个月

 

产品物理化学光谱特性

分子量：720.72

外观：固体

溶剂：DMSO

激发波长(nm)：N/A

发射波长(nm)：N/A

 

产品介绍

SoNa™ 520 是一种新型钠荧光指示剂染料，用于细胞和其他生物样品中的钠含量。 SoNa™ 520 是一种荧光染料，与钠离子结合后荧光强度大大增强。通过测量发射的荧光强度，研究人员可以评估生物样品中的钠离子浓度或研究钠离子在生物刺激下如何变化。与其他众所周知的荧光钠离子指示剂（例如 SBFI 和Corona Red）相比，它可能具有较高的灵敏度。它可用于测量活细胞和其他生物样品中钠浓度的变化。与常见的 SBFI 相比，SoNa™ 520 的灵敏度要高得多，在相同条件下具有更大的荧光响应。此外，SoNa™ 520 可以用可见 488 nm 激光或类似的可见光很好地激发，以避免激发 SBFI 所需的紫外线激发。紫外线激发会对细胞和其他生物样品造成损害，并且比可见光更快地光漂白染料探针。钠离子指示剂的使用使科学家能够研究与钠相关的各种生理过程，例如钠离子通道活性、细胞信号传导和钠稳态。 SoNa™ 520 提供了有关细胞机制的宝贵见解，可用xin脏病学和细胞生物学等领域。百萤生物是AAT Bioquest的中国代理商，为您提供优质的SoNa™ 520。 

 

溶解方案(溶剂以说明书为准)

	0.1 mg	0.5 mg	1 mg	5 mg	10 mg
1 mM	138.75 µL	693.751 µL	1.388 mL	6.938 mL	13.875 mL
5 mM	27.75 µL	138.75 µL	277.5 µL	1.388 mL	2.775 mL
10 mM	13.875 µL	69.375 µL	138.75 µL	693.751 µL	1.388 mL

 

参考文献

Sodium regulates PLC and IP3 R-mediated calcium signaling in invasive breast cancer cells.Authors: James, Andrew D and Unthank, Katherine P and Jones, Isobel and Sajjaboontawee, Nattanan and Sizer, Rebecca E and Chawla, Sangeeta and Evans, Gareth J O and Brackenbury, William JJournal: Physiological reports (2023): e15663

 

Cytosolic Sodium Influx in Mesophyll Protoplasts of Arabidopsis thaliana, wt, sos1:1 and nhx1 Differs and Induces Different Calcium Changes.Authors: Morgan, Sherif H and Kader, Md Abdul and Lindberg, SylviaJournal: Plants (Basel, Switzerland) (2022)

 

Off-target effects of sodium-glucose co-transporter 2 blockers: empagliflozin does not inhibit Na+/H+ exchanger-1 or lower [Na+]i in the heart.Authors: Chung, Yu Jin and Park, Kyung Chan and Tokar, Sergiy and Eykyn, Thomas R and Fuller, William and Pavlovic, Davor and Swietach, Pawel and Shattock, Michael JJournal: Cardiovascular research (2021): 2794-2806

 

Imaging of Local and Global Sodium Signals in Astrocytes.Authors: Gerkau, Niklas J and Kafitz, Karl W and Rose, Christine RJournal: Methods in molecular biology (Clifton, N.J.) (2019): 187-202

 

Relation between activity-induced intracellular sodium transients and ATP dynamics in mouse hippocampal neurons.Authors: Gerkau, Niklas J and Lerchundi, Rodrigo and Nelson, Joel S E and Lantermann, Marina and Meyer, Jan and Hirrlinger, Johannes and Rose, Christine RJournal: The Journal of physiology (2019): 5687-5705

 

Astrocyte Sodium Signalling and Panglial Spread of Sodium Signals in Brain White Matter.Authors: Moshrefi-Ravasdjani, Behrouz and Hammel, Evelyn L and Kafitz, Karl W and Rose, Christine RJournal: Neurochemical research (2017): 2505-2518

 

Rapid sodium signaling couples glutamate uptake to breakdown of ATP in perivascular astrocyte endfeet.Authors: Langer, Julia and Gerkau, Niklas J and Derouiche, Amin and Kleinhans, Christian and Moshrefi-Ravasdjani, Behrouz and Fredrich, Michaela and Kafitz, Karl W and Seifert, Gerald and Steinhäuser, Christian and Rose, Christine RJournal: Glia (2017): 293-308

 

Sodium influx through cerebral sodium-glucose transporter type 1 exacerbates the development of cerebral ischemic neuronal damage.Authors: Yamazaki, Yui and Harada, Shinichi and Wada, Tetsuyuki and Hagiwara, Teruki and Yoshida, Shigeru and Tokuyama, ShogoJournal: European journal of pharmacology (2017): 103-110

 

Differential effects of energy deprivation on intracellular sodium homeostasis in neurons and astrocytes.Authors: Gerkau, Niklas J and Rakers, Cordula and Petzold, Gabor C and Rose, Christine RJournal: Journal of neuroscience research (2017): 2275-2285

 

Comparison of fluorescence probes for intracellular sodium imaging in prostate cancer cell lines.Authors: Iamshanova, Oksana and Mariot, Pascal and Lehen'kyi, V'yacheslav and Prevarskaya, NataliaJournal: European biophysics journal : EBJ (2016): 765-777

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